The p70S6K antibody from Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to RPS6KB1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The p70S6K antibody has been validated for the following applications: EIA, Immunoassay, Precipitation, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation